frustrate

To disappoint or defeat; to vex by depriving of something expected or desired.

“It frustrates me to do all this work and then lose it all.”

To hinder or thwart.

“My clumsy fingers frustrate my typing efforts.”

To cause stress or annoyance.

“This test frustrates me because if I fail, it'll destroy my grade.”

Hinder or prevent (the efforts, plans, or desires) of

“What ultimately frustrated every challenger was Ruth's amazing September surge”

“foil your opponent”

Treat cruelly

“The children tormented the stuttering teacher”

Ineffectual; useless; fruitless.